Imagine a world you could take a snapshot of your brain, and then, after completing a task, you can then erase the memories of all the tasks completed. That is the concept behind the movie Paycheck.
With today’s technology and scientific advancements, this capability is not yet a reality; however, continuing advancements in the realm of neuropsychological studies, Ligand-Directed cell targeting, combined with the eccentric theories of a brilliant astrophysicist, that science fiction may someday be a reality.
I thought I would use this week’s University discussion to press our minds into the brink of reality. In doing so, please note, that while I am not claiming that we can erase memories with our current scientific knowledge, I am citing scientific studies and theoretical postulates that accrue support for my views that one day, it may be possible to erase memories.
In 2006, Mueller reviews the advancement of neurological studies for the underlying biology of memory formation, studies such as those being performed by Reissner, Shobe and Carew (Meuller, 2006). Regarding this study, Mueller states that “the demonstrated application of nodal analysis to a well investigated signaling pathway implicated in learning and memory elegantly demonstrates the potential to unravel complex molecular networks and to extract the essentials (Mueller, 2006).” Almost eight years prior, J.D.E. Gabrieli discussed the increasing capabilities of positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) to help identify portions of the brain that were active during learning and retrieval of specific types of memory (1998). Additionally, a purview of 40 years of neuroscience will show the significant strides we continue to make in the field of neurological studies (Kandel, 2009).
As scientific knowledge and technology advances, it will only become easier to identify the areas of the brain where memories are created and stored.
Frank Tipler, in his book The Physics of Christianity postulates his theories of the future of humanity. His views, based on theories around the Bekenstein Bound, baryon-annihilation and quantum computing, states that he believes humans will eventually be able to download copies of themselves into Artificial Intelligence constructs (Tipler, 2007).
Papers (which I really don’t claim to understand) around Ligand-Directed gene and cell targeting, outlines our current and growing capabilities around being able to target and address substances that meet certain biological criteria (Hajitou, et al., 2006).
Bringing all these current theories and studies into a synthesis, I propose that someday in the future, we may be able to tag and identify the current state of our memory through neurobiological methods, or make an imprint of what our current brain structure is like, right down to the atoms and molecules (Tipler, 2007). Upon taking a copy, we can then learn new concepts (such as the super-secret patented recipe for Coke or Pepsi). After the completion of our learning, we can either use future Ligand-Directed tagging to identify and target for destruction the changes in our neurology, or we might just prefer to restore ourselves to a previous state.
Sometimes, truth can be stranger than fiction.
Gabrieli, J. D. (1998). Cognitive Neuroscience of Human Memory. Annual Review of Psychology, 87-115.
Hajitou, A., Trepel, M., Lilley, C., Soghomonyan, S., Alauddin, M., Marini , F., . . . Arap , W. (2006). A Hybrid vector for ligand-directed tumor targeting and molecular imaging. CELL, 385 – 398.
Kandel, E. (2009). The Biology of Memory: A Forty-Year Perspective. The Journal of Neuroscience, 12748-12756.
Mueller, U. (2006). Memory: Cellular and molecular networks. Cellular and Molecular Life Sciences, 961 – 962.
Tipler, F. (2007). The Physics of Christianity. New York : Doubleday.